/ Dictionary / Index G guinea pig: Meaning and Definition of Find definitions for: guin'ea pig" Pronunciation: [key] a short-eared, tailless rodent of the genus Cavia, usually white, black, and tawny, commonly regarded as the domesticated form of one of the South American wild species of cavy: often used in scientific experiments or kept as a pet. the subject of any sort of experiment. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Guinea pepper guinea worm Related Content Daily Word Quiz: pudgy Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language