/ Dictionary / Index G guiro: Meaning and Definition of Find definitions for: gui•ro Pronunciation: (gwēr'ō Sp. gē'rô), [key] — pl. -ro. a South American musical instrument consisting of a hollow gourd with serrated surface that is scraped with a stick. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. guipure guisard Related Content Daily Word Quiz: reiterate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language