/ Dictionary / Index H half-life: Meaning and Definition of Find definitions for: half-life Pronunciation: (haf'līf", häf'-), [key] — pl. -lives the time required for one half the atoms of a given amount of a radioactive substance to disintegrate. the time required for the activity of a substance taken into the body to lose one half its initial effectiveness. a brief period during which something flourishes before dying out. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: half-life (Thesaurus) half-length half-light Related Content Daily Word Quiz: denizen Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language