/ Dictionary / Index H heartsick: Meaning and Definition of Find definitions for: heart•sick Pronunciation: (härt'sik"), [key] — adj. extremely depressed or unhappy. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: heartsick (Thesaurus) heart shell heartsome Related Content Daily Word Quiz: fabricate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language