/ Dictionary / Index H hepatomegaly: Meaning and Definition of Find definitions for: hep•a•to•meg•a•ly Pronunciation: (hep"u-tō-meg'u-lē, hi-pat"u-), [key] — n. Pathol. an abnormal enlargement of the liver, usually associated with liver disease or heart failure. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: hepatomegaly (Thesaurus) hepatoma hepatopancreas Related Content Daily Word Quiz: secular Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language