/ Dictionary / Index I ichthyosis: Meaning and Definition of Find definitions for: ich•thy•o•sis Pronunciation: (ik"thē-ō'sis), [key] — n. Pathol. a hereditary skin disease in which the epidermis continuously flakes off in large scales or plates. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: ichthyosis (Thesaurus) ichthyosaurus -ician Related Content Daily Word Quiz: punctual Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language