/ Dictionary / Index I infest: Meaning and Definition of Find definitions for: in•fest Pronunciation: (in-fest'), [key] — v.t. to live in or overrun to an unwanted degree or in a troublesome manner, esp. as predatory animals or vermin do: Sharks infested the coastline. to be numerous in, as anything undesirable or troublesome: the cares that infest the day. to harass. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: infest (Thesaurus) infertile infestation Related Content Daily Word Quiz: sequester Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language