/ Dictionary / Index I insufflate: Meaning and Definition of Find definitions for: in•suf•flate Pronunciation: (in-suf'lāt, in'su-flāt"), [key] — -flat•ed, -flat•ing. to blow or breathe (something) in. to blow (air or a medicinal substance) into some opening or upon some part of the body. to breathe upon, esp. upon one being baptized or upon the water of baptism. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: insufflate (Thesaurus) insufficient insula Related Content Daily Word Quiz: acquiesce Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language