/ Dictionary / Index I irregardless: Meaning and Definition of Find definitions for: ir•re•gard•less Pronunciation: (ir"i-gärd'lis), [key] — adv. Nonstandard. regardless. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: irregardless (Thesaurus) irreg. irregular Related Content Daily Word Quiz: acquiesce Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language