/ Dictionary / Index I irresponsive: Meaning and Definition of Find definitions for: ir•re•spon•sive Pronunciation: (ir"i-spon'siv), [key] — adj. not responsive; not responding, or not responding readily, as in speech, action, or feeling. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. irresponsible irretentive Related Content Daily Word Quiz: sequester Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language