/ Dictionary / Index I Isère: Meaning and Definition of Find definitions for: I•sère Pronunciation: (ē-zâr'), [key] — n. a river in SE France, flowing from the Alps to the Rhone River. 150 mi. (240 km) long. a department in SE France. 860,378; 3180 sq. mi. (8235 sq. km). Cap.: Grenoble. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: isere (Thesaurus) isentropic Iseult Related Content Daily Word Quiz: simian Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language