/ Dictionary / Index I Isis: Meaning and Definition of Find definitions for: I•sis Pronunciation: (ī'sis), [key] — n. a goddess of fertility, the sister and wife of Osiris and mother of Horus, and usually represented as a woman with a cow's horns with the solar disk between them: later worshiped in the Greek and Roman empires. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: isis (Thesaurus) isinglass Iskander Bey Related Content Daily Word Quiz: spectral Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language