/ Dictionary / Index I isthmus: Meaning and Definition of Find definitions for: isth•mus Pronunciation: (is'mus), [key] — pl. -mus•es, -mi a narrow strip of land, bordered on both sides by water, connecting two larger bodies of land. a connecting, usually narrow, part, organ, or passage, esp. when joining structures or cavities larger than itself. the narrow fleshy area between the sides of the lower jaw of a fish. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: isthmus (Thesaurus) Isthmian Games -istic Related Content Daily Word Quiz: spectral Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language