/ Dictionary / Index L lamebrain: Meaning and Definition of Find definitions for: lame•brain Pronunciation: (lām'brān"), [key] — n. Informal. a dunce; booby; fool. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. lame Lamech Related Content Daily Word Quiz: reclusive Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language