/ Dictionary / Index L La Serena: Meaning and Definition of Find definitions for: La Se•re•na Pronunciation: (lä se-re'nä), [key] a seaport in central Chile. 71,898. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. laser disk laser printer Related Content Daily Word Quiz: hedonist Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language