/ Dictionary / Index L lead-off: Meaning and Definition of Find definitions for: lead-off Pronunciation: (lēd'ôf", -of"), [key] — adj. leading off or beginning: the lead-off item on the agenda. lead•off Pronunciation: (lēd'ôf", -of"), [key] — n. an act that starts something; start; beginning. the player who is first in the batting order or who is first to bat for a team in an inning. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: lead-off (Thesaurus) lead monoxide lead oxide Related Content Daily Word Quiz: arboreal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language