/ Dictionary / Index L least significant digit: Meaning and Definition of Find definitions for: least' signif'icant dig'it Pronunciation: [key] the digit farthest to the right in a number. Abbr.: LSD Cf. most significant digit. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. least shrew least squares Related Content Daily Word Quiz: arboreal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language