/ Dictionary / Index L lethargize: Meaning and Definition of Find definitions for: leth•ar•gize Pronunciation: (leth'ur-jīz"), [key] — -gized, -giz•ing. to make lethargic; stupefy. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. lethargic encephalitis lethargy Related Content Daily Word Quiz: tenacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language