/ Dictionary / Index L lissome: Meaning and Definition of Find definitions for: lis•some Pronunciation: (lis'um), [key] — adj. lithesome or lithe, esp. of body; supple; flexible. agile, nimble, or active. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: lissome (Thesaurus) lisse lissotrichous Related Content Daily Word Quiz: mamba Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language