/ Dictionary / Index L loathsome: Meaning and Definition of Find definitions for: loath•some Pronunciation: (lō'sum, lōth'-), [key] — adj. causing feelings of loathing; disgusting; revolting; repulsive: a loathsome skin disease. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: loathsome (Thesaurus) loathly loaves Related Content Daily Word Quiz: resilient Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language