/ Dictionary / Index L loofah: Meaning and Definition of Find definitions for: loo•fah Pronunciation: (l'fu), [key] — n. Also called any of several tropical vines of the genus Luffa, of the gourd family, bearing large, elongated fruit. the fruit of such a vine. Also calledthe dried, fibrous interior of this fruit, used as a sponge. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: loofah (Thesaurus) loof looie Related Content Daily Word Quiz: agitated Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language