/ Dictionary / Index L lost cause: Meaning and Definition of Find definitions for: lost' cause' Pronunciation: [key] a cause that has been defeated or whose defeat is inevitable. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. lost Lost Colony Related Content Daily Word Quiz: prevalent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language