/ Dictionary / Index L Lyme disease: Meaning and Definition of Find definitions for: Lyme' disease" Pronunciation: (līm), [key] — Pathol. Pathol. an acute inflammatory disease caused by a tick-borne spirochete, Borrelia burgdorferi, characterized by recurrent episodes of decreasing severity in which joint swelling, fever, and rash occur, sometimes with cardiac or nervous system complications. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Lyman lyme-hound Related Content Daily Word Quiz: arboreal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language