/ Dictionary / Index L lyophilize: Meaning and Definition of Find definitions for: ly•oph•i•lize Pronunciation: (lī-of'u-līz"), [key] — -lized, -liz•ing. (of tissue, blood, serum, or the like) to dry by freezing in a high vacuum. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: lyophilize (Thesaurus) lyophilic lyophobic Related Content Daily Word Quiz: philtrum Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language