/ Dictionary / Index M mainliner: Meaning and Definition of Find definitions for: main•lin•er Pronunciation: (mān'lī"nur, -lī'-), [key] — n. a person who mainlines. a person who belongs to a mainline group. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. main line mainly Related Content Daily Word Quiz: pundit Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language