/ Dictionary / Index M manic-depressive: Meaning and Definition of Find definitions for: man•ic-de•pres•sive Pronunciation: (man'ik-di-pres'iv), [key] — Psychiatry. Psychiatry. —adj. suffering from bipolar disorder. —n. a person suffering from this disorder. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: manic-depressive (Thesaurus) manic manic-depressive illness Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language