/ Dictionary / Index M Melissa: Meaning and Definition of Find definitions for: Me•lis•sa Pronunciation: (mu-lis'u), [key] the sister of Amalthea who nourished the infant Zeus with honey. a female given name. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: melissa (Thesaurus) melisma Melitene Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language