/ Dictionary / Index M Melpomene: Meaning and Definition of Find definitions for: Mel•pom•e•ne Pronunciation: (mel-pom'u-nē"), [key] — n. Class. Myth. the Muse of tragedy. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: melpomene (Thesaurus) melos Melrose Related Content Daily Word Quiz: placid Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language