/ Dictionary / Index M Mesopotamia: Meaning and Definition of Find definitions for: Mes•o•po•ta•mi•a Pronunciation: (mes"u-pu-tā'mē-u), [key] — n. an ancient region in W Asia between the Tigris and Euphrates rivers: now part of Iraq. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: mesopotamia (Thesaurus) mesoplankton mesorectum Related Content Daily Word Quiz: panacea Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language