/ Dictionary / Index M mestizo: Meaning and Definition of Find definitions for: mes•ti•zo Pronunciation: (me-stē'zō, mi-), [key] — pl. -zos, -zoes. a person of racially mixed ancestry, esp., in Latin America, of mixed American Indian and European, usually Spanish or Portuguese, ancestry, or, in the Philippines, of mixed native and foreign ancestry. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: mestizo (Thesaurus) mestiza mestranol Related Content Daily Word Quiz: pristine Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language