/ Dictionary / Index M methadone: Meaning and Definition of Find definitions for: meth•a•done Pronunciation: (meth'u-dōn"), [key] — n. Pharm. a synthetic narcotic, CHClNO, similar to morphine but effective orally, used in the relief of pain and as a heroin substitute in the treatment of heroin addiction. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: methadone (Thesaurus) methacrylic acid methaemoglobin Related Content Daily Word Quiz: cautious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language