/ Dictionary / Index M missis: Meaning and Definition of Find definitions for: mis•sis Pronunciation: (mis'iz, -is), [key] — n. wife: I'll have to ask the missis. the mistress of a household. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: missis (Thesaurus) Mission Viejo missish Related Content Daily Word Quiz: philtrum Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language