mono: Meaning and Definition of

mon•o

1. infectious mononucleosis.

mon•o

1. monophonic (def. 2).

mono-

1. a combining form meaning “alone,” “single,” “one” (monogamy); specialized in some scientific terms to denote a monomolecular thickness (monolayer) and adapted in chemistry to apply to compounds containing one atom of a particular element (monohydrate).