/ Dictionary / Index M monogenesis: Meaning and Definition of Find definitions for: mon•o•gen•e•sis Pronunciation: (mon"u-jen'u-sis), [key] — n. the hypothetical descent of the human race from a single pair of individuals. the hypothetical descent of all living things from a single cell. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: monogenesis (Thesaurus) monogenean monogenetic Related Content Daily Word Quiz: abdicate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language