/ Dictionary / Index M monohybrid: Meaning and Definition of Find definitions for: mon•o•hy•brid Pronunciation: (mon"u-hī'brid), [key] — Genetics. Genetics. —n. the offspring of individuals that differ with respect to a particular gene pair. Also calleda genetic cross made to examine the distribution of one specific set of alleles in the resulting offspring. —adj. of or pertaining to such an offspring. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: monohybrid (Thesaurus) monohull monohydrate Related Content Daily Word Quiz: digression Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language