/ Dictionary / Index M M.S.H.E.: Meaning and Definition of Find definitions for: M.S.H.E. Pronunciation: [key] Master of Science in Home Economics. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. M.S.H.A. M-shell Related Content Daily Word Quiz: diligent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language