/ Dictionary / Index M myxedema: Meaning and Definition of Find definitions for: myx•e•de•ma Pronunciation: (mik"si-dē'mu), [key] — n. Pathol. a condition characterized by thickening of the skin, blunting of the senses and intellect, and labored speech, associated with hypothyroidism. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: myxedema (Thesaurus) myxasthenia myxo- Related Content Daily Word Quiz: censure Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language