/ Dictionary / Index O Old Spanish Trail: Meaning and Definition of Find definitions for: Old' Span'ish Trail' Pronunciation: [key] — Amer. Hist. Amer. Hist. an overland route from Santa Fe, N. Mex., to Los Angeles, Calif., first marked out in 1776 by Spanish explorers and missionaries. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Old Spanish old squaw Related Content Daily Word Quiz: loquacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language