/ Dictionary / Index O Oto-Manguean: Meaning and Definition of Find definitions for: O•to-Man•gue•an Pronunciation: (ō"tō-mäng'gē-un, -mang'-), [key] — n. a family of American Indian languages spoken in central and southern Mexico, including Mixtec, Zapotec, and Otomi. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. otology Otomi Related Content Daily Word Quiz: rustic Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language