/ Dictionary / Index P pepsin: Meaning and Definition of Find definitions for: pep•sin Pronunciation: (pep'sin), [key] — n. Biochem. an enzyme, produced in the stomach, that in the presence of hydrochloric acid splits proteins into proteoses and peptones. a commercial form of this substance, obtained from the stomachs of hogs, used as a digestive, as a ferment in the manufacture of cheese, etc. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: pepsin (Thesaurus) pep rally pepsinate Related Content Daily Word Quiz: modify Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language