/ Dictionary / Index P pestilence: Meaning and Definition of Find definitions for: pes•ti•lence Pronunciation: (pes'tl-uns), [key] — n. a deadly or virulent epidemic disease. See something that is considered harmful, destructive, or evil. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: pestilence (Thesaurus) pestiferous pestilent Related Content Daily Word Quiz: secular Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language