/ Dictionary / Index P picker-upper: Meaning and Definition of Find definitions for: pick•er-up•per Pronunciation: (pik'ur-up'ur), [key] — n. Informal. something that restores one's depleted energy or depressed spirits; pick-me-up. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. pickeringite picket Related Content Daily Word Quiz: careening Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language