/ Dictionary / Index P point mutation: Meaning and Definition of Find definitions for: point' muta"tion Pronunciation: [key] — Genetics. Genetics. a change in a single base in a nucleotide sequence. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. point man point of articulation Related Content Daily Word Quiz: morose Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language