/ Dictionary / Index P polytene chromosome: Meaning and Definition of Find definitions for: pol'y•tene chro"mosome Pronunciation: (pol'ē-tēn"), [key] — Genetics. Genetics. a giant, cross-banded chromosome that results from multiple replication of its genetic material with the duplicated chromatin strands remaining closely associated. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. polytechnic polytetrafluoroethylene Related Content Daily Word Quiz: serendipity Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language