/ Dictionary / Index P Poughkeepsie: Meaning and Definition of Find definitions for: Pough•keep•sie Pronunciation: (pu-kip'sē), [key] — n. a city in SE New York, on the Hudson. 29,757. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. pouf Pouilly Related Content Daily Word Quiz: frugal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language