/ Dictionary / Index P powerless: Meaning and Definition of Find definitions for: pow•er•less Pronunciation: (pou'ur-lis), [key] — adj. unable to produce an effect: a disease against which modern medicine is virtually powerless. lacking power to act; helpless: His legs crumpled, and he was powerless to rise. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: powerless (Thesaurus) powerhouse power line Related Content Daily Word Quiz: opulent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language