/ Dictionary / Index P pox: Meaning and Definition of Find definitions for: pox Pronunciation: (poks), [key] — n. Pathol. a disease characterized by multiple skin pustules, as smallpox. syphilis. Also calleda disease of sweet potatoes, characterized by numerous pitlike lesions on the roots, caused by a fungus, Streptomyces ipomoea. (used interjectionally to express distaste, rejection, aversion, etc.): A pox on you and your bright ideas! Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: pox (Thesaurus) Powys poxvirus Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language