/ Dictionary / Index P prefecture: Meaning and Definition of Find definitions for: pre•fec•ture Pronunciation: (prē'fek-chur), [key] — n. the office, jurisdiction, territory, or official residence of a prefect. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: prefecture (Thesaurus) prefectorial prefecture apostolic Related Content Daily Word Quiz: careening Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language