/ Dictionary / Index P Presque Isle: Meaning and Definition of Find definitions for: Presque Isle Pronunciation: (presk" īl'), [key] a city in NE Maine. 11,172. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. pres. part. press Related Content Daily Word Quiz: simian Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language