/ Dictionary / Index P primary syphilis: Meaning and Definition of Find definitions for: pri'mary syph'ilis Pronunciation: [key] — Pathol. Pathol. the first stage of syphilis, characterized by the formation of a chancre at the site of infection. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. primary stress primary tissue Related Content Daily Word Quiz: resilient Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language